ea0041ep863 | Pituitary - Basic | ECE2016
Raggi Francesco
, Russo Dania
, Urbani Claudio
, Cappellani Daniele
, Manetti Luca
, Sardella Chiara
, Lupi Isabella
, Scattina Ilaria
, Tomisti Luca
, Marcocci Claudio
, Martino Enio
, Bogazzi Fausto
Introduction: Polychlorinated biphenyls (PCBs) are environmental pollutants that modulate endocrine functions, induce tumorigenesis, and regulate apoptosis in several tissues; however, their effects on the apoptosis of pituitary cells is unknown.The aim of this study was to evaluate the PCBs influence on the apoptosis of normal pituitary cells and elucidate the molecular mechanisms involved.Methods: Primary cell cultures from mouse...